Skin Substitutes-What’s New in 2025? Important CMS Updates and How Revantage Healthcare Can Assist

Navigating the ever-changing policies around skin substitutes can be challenging for healthcare 
providers. With new updates for 2025 introduced by the Centers for Medicare and Medicaid Services 
(CMS), staying compliant and efficient is more important than ever. At Revantage Healthcare, we 
specialize in managing the complexities of wound care billing, ensuring you stay ahead of the curve. 

CMS Updates on Skin Substitutes for 2025

Now known as Cellular and/or Tissue Based Products (CTPs), these repurposed and re-engineered products fall under the Tissue Engineering Products category. The CMS is updating policy structures across all healthcare services in phases – here’s what you need to know.

1. Nationwide Local Coverage Determinations (LCDs)

Also, Medicare contractors estimated to include policies will be effective from February 11, 2025, as follows:

Replacing vague comments such as ‘Failure to respond’ with agreeable statements ‘50% ulcer area reduction’ as a target. Increasing application limits between 4 to 8 and extending the duration range to between 12 and 16 weeks. providing guidelines for vascular assessment and contraindication of appropriate therapies.

2. Modifier Requirements

The Centers for Medicare Services has updated the billing modifier requirements to define them more deliberately.

KX Modifier: For more than four applications during the treatment period.

JW Modifier: Documents portions of products that have been purchased but not used, as in the case with single use products. 

JZ Modifier: Certifies that there was no waste that occurred during the course of the procedure.

3. High-Cost vs Low-Cost Classification

CTPs remain classified as high-cost or low-cost for reimbursement purposes. The high-cost products are linked to CPT codes 15271–15278, while low cost products correspond to HCPCS codes C5271–C5278. These classifications ensure appropriate payment under both the Physician Fee Schedule (PFS) and the Outpatient Prospective Payment System (OPPS). 

How Revantage Healthcare make Wound Care Billing Easy

Wound care billing could be a headache but not with Revantage Healthcare. We offer a solution for your billing from claim submissions to compliance so that you can take care of your patients. Working with wound care billing can be quite difficult, and that is why Revantage Healthcare works to make it easier for you. We manage each part of your billing cycle, right from submitting the claims and complying, to allowing you to shift your focus to your patients.

Services Include:

Accurate Billing and Coding: Ensuring correct documentation and use of modifiers like -KX, 

JW, and JZ. 

Compliance Expertise: Staying updated on CMS policies, including LCDs and HCPCS 

classifications. 

∙Comprehensive Documentation Support: From wound measurements to justification for 

repeated applications. 

Streamlined Claim Submissions: Managing appeals and follow-ups for timely 

reimbursements. 

Stay Ahead of CMS Changes with Revantage Healthcare

The 2025 updates to skin substitutes billing policies highlight the need for precision and expertise. At 
Revantage Healthcare, we not only simplify the billing process but also ensure you maximize your 
reimbursements while staying compliant. 
Contact us today to learn how we can manage all your wound care billing hassles and let you focus 
on delivering exceptional care. 
Facebook
Twitter
LinkedIn
WhatsApp
Picture of Ronnie
Ronnie

Leave a Reply

Your email address will not be published. Required fields are marked *