ICD-10 Codes for Acute Kidney Injury (AKI) | Medical Coding Guide 2025

Acute Kidney Injury (AKI), also known as acute renal failure, is a critical condition in which kidneys suddenly stop functioning. Correct ICD-10 coding for kidney diseases is essential for proper diagnosis, billing, and insurance reimbursements. This comprehensive guide by Revantage Healthcare provides a deep dive into the latest ICD-10 codes for AKI, chronic kidney diseases, and related conditions, ensuring accuracy and compliance in medical coding.

What is Acute Kidney Injury (AKI)?

Acute Kidney Injury (AKI) is a sudden deterioration in kidney function, commonly triggered by dehydration, infection, medication toxicity, or underlying chronic kidney issues. The correct ICD 10 code for AKI depends on the underlying cause and associated renal complications.

Common terms associated with AKI include:

  • ICD 10 AKI

  • Acute kidney injury ICD 10

  • ICD 10 code acute kidney injury

  • Acute kidney injury ICD 10 code

  • AKI ICD 10 code

aki icd 10 Codes

ICD-10 Codes for Acute Kidney Failure (N17 series)

The ICD-10 coding system classifies AKI under the N17 category. Coders should select specific subtypes based on physician documentation:

  • N17.0: ICD 10 code for acute kidney failure with tubular necrosis

  • N17.1: ICD 10 code for acute kidney failure with acute cortical necrosis

  • N17.2: ICD 10 code for acute kidney failure with medullary necrosis

  • N17.8: ICD 10 code for other acute kidney failure

  • N17.9: ICD 10 code for acute kidney injury unspecified

Alternate search terms include:

  • ICD 10 code for acute renal failure

  • ICD 10 code for acute kidney failure unspecified

  • ICD 10 code for unspecified acute kidney failure

Coding Acute on Chronic Renal Failure

When AKI occurs in a patient with underlying chronic kidney disease (CKD), use a combination of codes to capture both conditions.

Examples include:

  • ICD 10 code for acute on chronic renal failure

  • ICD 10 code for acute renal failure with chronic kidney disease

  • ICD 10 code for acute kidney injury with chronic kidney disease

  • ICD 10 code for acute kidney injury with CKD

Common CKD-related codes:

  • N18.3: ICD 10 code for CKD stage 3

  • N18.4: ICD 10 code for CKD stage 4

  • N18.5: ICD 10 code for CKD stage 5

  • N18.6: ICD 10 code for end stage renal disease (ESRD)

Long-tail combinations:

  • ICD 10 code for acute kidney injury with CKD stage 3

  • ICD 10 code for acute kidney injury with CKD stage 4

  • ICD 10 code for acute kidney injury with CKD stage 5

  • ICD 10 code for acute kidney injury with end stage renal disease

  • ICD 10 code for acute kidney injury with ESRD

Secondary Causes of AKI and Their ICD-10 Combinations

Coders often face challenges when AKI is caused by secondary conditions. Below are examples of how to document and code those accurately:

AKI due to Medical Conditions:

  • ICD 10 code for acute kidney injury due to sepsis

  • ICD 10 code for acute kidney injury due to hypotension

  • ICD 10 code for acute kidney injury due to dehydration

  • ICD 10 code for acute kidney injury due to infection

  • ICD 10 code for acute kidney injury due to trauma

  • ICD 10 code for acute kidney injury due to shock

  • ICD 10 code for acute kidney injury due to heart failure

  • ICD 10 code for acute kidney injury due to liver failure

  • ICD 10 code for acute kidney injury due to pancreatitis

  • ICD 10 code for acute kidney injury due to burns

AKI due to Medications & Toxic Agents:

  • ICD 10 code for acute kidney injury due to medication

  • ICD 10 code for acute kidney injury due to nephrotoxic drugs

  • ICD 10 code for acute kidney injury due to ACE inhibitors

  • ICD 10 code for acute kidney injury due to contrast

  • ICD 10 code for acute kidney injury due to rhabdomyolysis

  • ICD 10 code for acute kidney injury due to hemolysis

  • ICD 10 code for acute kidney injury due to multiple organ failure

AKI due to Obstruction:

  • ICD 10 code for acute kidney injury due to urinary tract obstruction

  • ICD 10 code for acute kidney injury due to kidney stones

  • ICD 10 code for acute kidney injury due to prostate enlargement

  • ICD 10 code for acute kidney injury due to bladder obstruction

  • ICD 10 code for acute kidney injury due to ureteral obstruction

Rare Causes and Autoimmune-Linked AKI

  • ICD 10 code for acute kidney injury due to vasculitis

  • ICD 10 code for acute kidney injury due to glomerulonephritis

  • ICD 10 code for acute kidney injury due to interstitial nephritis

  • ICD 10 code for acute kidney injury due to lupus nephritis

  • ICD 10 code for acute kidney injury due to scleroderma

  • ICD 10 code for acute kidney injury due to amyloidosis

  • ICD 10 code for acute kidney injury due to thrombotic microangiopathy

  • ICD 10 code for acute kidney injury due to hemolytic uremic syndrome

  • ICD 10 code for acute kidney injury due to multiple myeloma

  • ICD 10 code for acute kidney injury due to renal artery stenosis

  • ICD 10 code for acute kidney injury due to renal vein thrombosis

Dialysis and Renal Replacement Therapy

When a patient with AKI undergoes dialysis or renal replacement therapy (RRT), coding should reflect this intervention:

  • ICD 10 code for acute kidney injury with dialysis

  • ICD 10 code for acute kidney injury with renal replacement therapy

How to Code AKI with CKD in Real-World Scenarios

Medical coders often ask, “how to code AKI with CKD?” The answer involves assigning codes for both acute and chronic components based on the clinical documentation.

Example:
A patient presents with AKI due to dehydration on top of CKD stage 3. Use:

  • N17.9 for acute kidney failure unspecified

  • N18.3 for CKD stage 3

  • Add E86.0 for dehydration if documented

Why Accurate Coding Matters

Precise ICD-10 coding is vital for:
✔️ Correct diagnosis classification
✔️ Maximum reimbursement
✔️ Minimizing claim rejections
✔️ Legal compliance
✔️ Patient care optimization

At Revantage Healthcare, we offer specialized ICD-10 medical coding for nephrology, ensuring accuracy, audit-readiness, and revenue integrity. Our certified professionals stay updated on evolving coding guidelines, including AKI, CKD, ESRD, and dialysis.

👉 Explore our medical billing and coding services

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